The Interview: Sister Helen Prejean. The Panel: Jennifer Granholm, Doug Heye, Lawrence Wilkerson. Mid-Show Guest: Talib Kweli.

Esquire TV's "The Runner-Up" star Clay Aiken, "The Story" author Judith Miller, "Thomas Jefforson" author Jon Meacham, CNBC chief international correspondent Michele Caruso Cabrera, Center for American Progress president Neera Tanden.

EPA Administrator Gina McCarthy, Georgetown professor Michael Eric Dyson, "The Selfie Vote" author Kristen Soltis Anderson, "End of Discussion" co-writer Mary Katherine Ham, and "Trainwreck" director & "Sick in the Head" author Judd Apatow.

"Pretty Ladylike" author Senator Claire McCaskill (D-MO), WTF's Marc Maron, Rep. Donna Edwards (D-MD), "Conservatarian Manifesto" author Charles Cooke, "The Blue Zones Solution" author Dan Buettner.

"A Fighting Chance" author Senator Elizabeth Warren (D-MA), "Live Right and Find Happiness" author Dave Barry, "In Defense of Liberal Education" author Fareed Zakaria, "Bad Religion" author Ross Douthat and Roll Call editor-in-chief Christina Bellantoni.

Bill's guests include comedy legend Billy Crystal, MSNBC "Now" host Alex Wagner, Ex-Rhode Island Governor Lincoln Chafee, consumer advocate Erin Brockovich, and ESPN commentator Will Cain.

GOP Presidential candidate & Ex-Senator Rick Santorum (R-PA), Representative Dana Rohrabacher (R-CA), Ex-State Senator Wendy Davis (D-TX), Washington Post national reporter Robert Costa and Senior Editor for The Daily Beast Michael Weiss.

Bill's guests include "Inside Out" actor Lewis Black, ex-representative Rick Lazio (R-NY), ex-senior CIA and FBI official Philip Mudd, ex-Ohio state senator Nina Turner (D-OH), and "Superpower" author Ian Bremmer.

Bill's guests include Democratic President hopeful, Senator Bernie Sanders (I-VT), Representative Luis Gutiérrez (D-IL), "¡Adios America!" author Ann Coulter, MSNBC contributor Joy Reid and Daily Caller's senior contributor Matt Lewis.

This weeks guests include comedy legend Mel Brooks, Representative Joaquin Castro (D-TX), "Citizenfour" director Laura Poitras, BBC World News anchor Kitty Kay, and "The Entrepreneurial Instinct" author Monica Mehta.

Bill's guests include "Jeff Ross Roasts Criminals" comic Jeff Ross, actor and environmentalist Ed Begley Jr., Daily Beast columnist Ron Christie, The Other 98% director Alexis Goldstein, and Slate's "The Gist" host Mike Pesca.

The Interview: Michael Mann. The Panel: Mary Matalin, Steve Schmidt, Lt. Governor Gavin Newsom (D-CA). Mid-Show Guest: Caitlin Flanagan.

Comedy legend Jay Leno, literary icon Salman Rushdie, Ex-HP CEO Carly Fiorina, Chris Hardwick and Paul Begala.

Celebrity chef & "Fresh Off the Boat" author Eddie Huang, activist Robert F. Kennedy, Jr., Daily Beast contributor Ana Marie Cox, Weekly Standard senior editor Christopher Caldwell, and G.O.P. consultant Liz Mair.

Bill's guests include film-maker & "Carsick" author John Waters, "Heretic" author Ayaan Hirsi Ali, Democratic president Heather McGhee, and "By the People" author Charles Murray.

Ex-Governor Howard Dean (D-VT), comedian and "Black and White" actor Bill Burr, "America in Retreat" author Bret Stephens, Washington Post's Nia-Malika Henderson, and The Atlantic's James Fallows.

Director Rob Reiner, singer/songwriter Aloe Blacc, Bill Nye "The Science Guy", writer Fran Lebowitz and Washington Post's Elahe Izadi.

Bill's guests include Ex-Obama guru & "Believer" author David Axelrod, "Going Clear" author Lawrence Wright, "American Crime" creator John Ridley, Heritage Foundation's daily signal Genevieve Wood, and author and journalist Matt Taibbi.

Bill's guests include "The Great Divide" author Joseph Stiglitz, Human Rights Foundation chairman Garry Kasparov, Wilson Center President and Ex-Representative Jane Harman (D-CA), New Yorker staff writer Adam Gopnik and Foreign Policy Initiative co-founder Dan Senor.

This weeks guests include director of "Merchants of Doubt" Robert Kenner, former Republican member of the United States House of Representatives Tom Davis, Editor-in-Chief for the Economist magazine Zanny Minton Beddoes, co-founder of the black political blog Jack and Jill Politics and CEO of Cultivated Wit Baratunde Thurston, and actor and author of "Holy Cow" David Duchovny.

Huffington Post's Editor-in-Chief Arianna Huffington, "Stonewalled" author Sharyl Attkisson, The National Review's Tom Rogan, The Hunting Ground's Annie Clark & Andrea Pino and actor Sean Penn.

Interview: "God, Guns, Grits, and Gravy" author Mike Huckabee. Panel: "The Slap" star Zachary Quinto, "Frank" author and ex-Rep. Barney Frank (D-MA), and CNN commentator S.E. Cupp. Panel Guest: NASA JPL Senior Water Scientist Professor Jay Famiglietti.

Interview: NBC and MLB sportscasting legend Bob Costas. Panel: ex-US Rep. Jack Kingston (R-GA), ex-NYC Council Speaker Christine Quinn, GOP Strategist Mercedes Schlapp. Panel Guest: "God's Bankers" author Gerald Posner.

This weeks guests include "Course in Miracles" author Marianne Williamson, "Blaze" anchor Amy Holmes, "Weekly Standard" writer John McCormack, "Redefining Realness" author Janet Mock, and British writer and journalist Johann Hari.

Bill's guests include Oscar winning director Kathryn Bigelow, "Wedding Ringer" actor Josh Gad, "Being Mortal" author Atul Gawande, New York Times "Upshot" correspondent Josh Barro, "The Work: My Search For a Life That Matters" author Wes Moore.