Based on the real case "Las Poquianchis". Dr. Sofía Capellán tells DIEM about the renowned case of "Las Cotuchas", three sisters who owned a brothel where they instigated murders and mistreatment of their sexual servants, who were forced to work there.

Irma, a girl who loves fish, is married to Alfonso, a concert pianist much older than her. Her marriage full of violence and humiliation clouds Irma's judgment, leading her to think that there is no way out of her terrible situation.

Elena moves to Pablo and his wife Claudine's house due to the convalescence she suffers thanks to a fall. The unhealthy love that Elena feels for her brother Pablo causes her to commit something crazy trying to defend him.

Hilario, Azucena's grandfather, sells her to Mr. Gregorio to be his wife in exchange for a small monthly payment to be able to survive in the town. Azucena, tired of the abuse her husband gives her, decides to put a stop to the situation.

Luz Blanco dedicated herself to murdering her 4 husbands in order to collect her insurance policies and avoid financial problems. Now, she teaches this lifestyle to her daughter Norma and her granddaughter Estela.

Eliana has had a lesbian romance with Joana at school, although she never accepts her homosexuality. Now older, and sublimating that love for her, she has married Franco, Joana's brother. Things get complicated when Joana, assumed without problems, reappears.

Mercedes and Elvira move to Mexico City to improve their quality of life. When Mercedes realizes that her husband Domingo is sexually abusing her daughter Lupita, she decides to take revenge.

Dr. Sofía Capellán and her team address the famous Van Diryk case that occurred in 1965, where Ana Gallardo is presumed to have killed the Count of Beltrán Peña, husband of her daughter Annete Van Diryk, to protect her from his mistreatment.

Thelma, tired of the cynicism and boring life she has with her husband Enrique, looks for a change in her life. One day she hatches an ingenious plan to be able to murder her husband and collect the life insurance to give herself a great life.

A married man with a family falls in love with a transgender women at a strip club and willing to do anything for her, for he is blindly in love with "her" until everything starts to fall apart all in violence.

Marta has a relationship with her stepfather from which she becomes pregnant. She finds out that he plans to abandon his family for business and decides to kill him, taking advantage of his mother's psychiatric condition.

María is a religious fanatic who has the idea that the devil has taken over her daughter, unlike her youngest son, who thinks he is an angel. In the name of her religion, María commits an unforgivable act.

Luz Mercedes lives tormented by the infidelities of her husband Amado. Luz María, Amado's ex-lover, becomes obsessed with the idea of ​​them getting back together. They both decide to take revenge against the person who hurt them.

Based on the real case "La Mataviejitas". Maggie was seriously affected since her grandmother abused and sold her at 14 years old; As a result, she murders the elderly women who are pensioners at the institution where she works..