Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more; illustrious guest: fellow Bronx native Congresswoman Alexandria Ocasio-Cortez. Series premiere.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more; illustrious guest: Don Cheadle.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more; illustrious guests: Vince Staples and John Legend.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more; illustrious guests: Ben Stiller and 2 Chainz.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more; illustrious guests: Lupita Nyong’o, Winston Duke & Sen. Kirsten Gillibrand (D-NY).

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more; illustrious guests: Carmelo Anthony and Jordan Peele.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more; illustrious guest: Issa Rae.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more; illustrious guests: Stacey Abrams and Anna Kendrick.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more; illustrious guest Sen. Cory Booker (D-NJ).

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more; illustrious guest: Seth Rogen.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Lil Nas X, and a special appearance by Paul Scheer.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Charlize Theron.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guests: Wu-Tang Clan.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Bill Hader.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Amy Poehler.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Gabrielle Union.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Ava DuVernay.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guests: Spike Lee and Matt Walsh.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Pete Buttigieg

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Lin-Manuel Miranda

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Regina Hall

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: ScHoolboy Q

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Anthony Anderson

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Ice Cube

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Zendaya

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: David Letterman.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Alexandria Ocasio-Cortez.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Penn Badgley.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Lakeith Stanfield.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Maxine Waters

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: John Mulaney.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Killer Mike.

Illustrious guest: Missy Elliott.

Illustrious guest: Nick Kroll.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Wale.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Seth Meyers

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more, now coming to you from their own homes. Illustrious guest: Dr. Anthony Fauci

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more, now coming to you from their own homes. Illustrious guest: John Legend

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more, now coming to you from their own homes. Illustrious guest: Malcolm Gladwell

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more, now coming to you from their own homes. Illustrious guest: Tracee Ellis Ross

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more, now coming to you from their own homes. Illustrious guest: Mark Cuban

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more, now coming to you from their own homes. Illustrious guest: Joe Biden

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more, now coming to you from their own homes. Illustrious guest: Alicia Keys

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more, now coming to you from their own homes. Illustrious guest: Chef José Andrés.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more, now coming to you from their own homes. Illustrious guests: Spike Jonze and Beastie Boys

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more, now coming to you from their own homes. Illustrious guest: Billy Porter

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more, now coming to you from their own homes. Illustrious guest: Dr. Nina

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more, now coming to you from their own homes. Illustrious guest: Katie Porter

Illustrious guest: Stacey Abrams

Illustrious guest: Freddy Gibbs

Illustrious guest: Jazmine Sullivan

Illustrious guest: Whoopi Goldberg

Illustrious guests: Zendaya & John David Washington English

Illustrious guest: Anthony Mackie

Illustrious guest: Ludacris

Illustrious guest: Kelly Rowland

Illustrious guest: Travis "Taco" Bennett

Illustrious guest: Ramy Youssef

Illustrious guest: Delroy Lindo

Illustrious guest: Eddie Huang

Illustrious guest: Phoebe Bridgers

Illustrious guest: Eddie Murphy

Illustrious guest: 24kGoldn

Illustrious guest: Kenan Thompson

Illustrious guest: Glenn Close

Illustrious guest: Andra Day

Illustrious guest: Miguel

Illustrious guest: J Balvin

Illustrious guest: Issa Rae

Illustrious guest: Demi Lovato

Illustrious guest: Julian Edelman

Illustrious guest: Taylour Paige

Illustrious guest: Yo-Yo Ma

Desus Nice and The Kid Mero go in on the news and cultural stories from the past week. Plus, correspondents Rainey and Tawanda see whether Desus & Mero can tell if strangers on the street are really from New York. Illustrious guest: Denzel Washington. Season premiere.

Desus Nice and The Kid Mero go in on the news and cultural stories from the past week. Plus, Desus & Mero take a look at the world of modern art, roasting some non-fungible tokens (NFTs) and trying to guess how much money they've been sold for. Illustrious guests: Tom Holland and Mark Wahlberg.

Desus Nice and The Kid Mero go in on the news and cultural stories of the past week. In search of even more hardware for their award-winning television show, Desus & Mero enlist American Cornhole League pro Lori Dool to help turn them into champions. After an intense training session, they take on a team of ringers from Long Island. Will Desus & Mero pull off the upset and add a new trophy to their shelf? Illustrious guest: Samuel L. Jackson.

Desus Nice and The Kid Mero go in on the news and cultural stories of the past week. Then, in the wake of rap star Pusha T's recent fast food endorsement, Desus & Mero conduct a blind taste test to find the best fish sandwich on the market. It's a test of both the sandwiches' flavor and the hosts' stomachs' endurance. Illustrious guest: Pusha T.

Desus Nice and The Kid Mero go in on the news and cultural stories of the past week. Then, the two hosts are tested on their knowledge of reality dating show stars. Can they distinguish a contestant who is "too hot to handle" from one who got married at first sight? Either way, the brand is strong and it's here for the right reasons. Illustrious guest: Michelle Yeoh.

Desus Nice and The Kid Mero go in on the news and cultural stories from the past week. Then, with the help of Karleen Roy, event planner to the stars, Desus & Mero prepare to throw Rihanna the greatest baby shower of all time. She has no idea that this event is in the works, but Desus & Mero hope that by planning an incredible party, they can get her to show up. Illustrious guest: Damson Idris.

Desus Nice and The Kid Mero go in on the news and cultural stories from the past week. Plus, correspondents Rainey and Tawanda ask people on the street if they've ever cheated on their partners and then see if Desus & Mero can spot the cheaters - some of whom share wild stories. Illustrious guest: Earl Sweatshirt.

Desus Nice and The Kid Mero go in on the news and cultural stories from the past week. Plus, John Wilson (How To With John Wilson) joins Desus & Mero at a local junk store to pick out some new decor for their offices. Wilson is an expert at finding beauty in unexpected places, and he helps Desus & Mero find the most precious treasure of all: friendship. Illustrious guest: Jon Bernthal.

Desus Nice and The Kid Mero go in on the news and cultural stories from the past week. Plus, Desus & Mero are inspired by a Bay Area kindergarten class's pep talk hotline to create a phone line of their own. They enlist some New York City kids to record discouraging messages for grownups, and Abbott Elementary star Janelle James stops by to help out.

Desus Nice and The Kid Mero go in on the news and cultural stories from the past week. Then, Desus & Mero throw the surprise baby shower they've been organizing for Rihanna with the help of celebrity event planner Karleen Roy. Celebrity attendees include CBS News legend Maurice DuBois. The decorations are spectacular and the places are set at the banquet table...but will Rihanna make an appearance? Illustrious guest: Quinta Brunson.

Desus Nice and The Kid Mero go in on the news and cultural stories from the past week. Then, Kenan Thompson from Saturday Night Live joins Desus & Mero to taste test several brands of bottled water, including one that costs over $1,000. They'll see if they can tell whether they're sipping pricey imported spring water or plain old New York City tap water. Can Desus, Mero and Kenan guess how much each bottle costs by the taste or is it all just...water to them?

Desus Nice and The Kid Mero go in on the news and cultural stories from the past week. Then, Desus & Mero take a look at some of the most lavish celebrity homes currently for sale and try to guess who they belong to. Will the decor provide enough information for them to correctly identify the sellers? Illustrious guest: Sam Jay.

Desus Nice and The Kid Mero go in on the news and cultural stories from the past week. Plus, in a new segment called "What's Your Damage?" correspondent Heben Nigatu opens an amateur therapist's office in a New York City park to find out what is wrong with the men of NYC. Desus and Mero try to guess what each guy's big problem is. Illustrious guest: Wanda Sykes.

Desus Nice and The Kid Mero go in on the news and cultural stories from the past week. Then, Seth Meyers (of NBC's Late Night with Seth Meyers) joins Desus & Mero on a trip Times Square to enjoy some elaborate, Texas-sized cocktails. Seth is known for conducting hilarious day-drinking interviews on his show, but these ridiculous beverages will put his tolerance to the test. Guest: Seth Meyers.

Desus Nice and The Kid Mero go in on the news and cultural stories from the past week. Plus, they sit down for a conversation with New York Yankees legend Derek Jeter covering everything from his most memorable moments on the field to the specific things he used to whisper to opposing teams' first basemen. Then, Desus and Mero want to help their office's floundering softball team turn their season around, so they ask football analyst Mina Kimes to help break down some game footage. Illustrious guest: Derek Jeter.