Blake asks Glenn to coach him through a new romantic relationship. Chief and Cat prank call Sy. Guest stars include Lindsay Sloane, James Adomian, Paul Scheer, Nick Offerman, Jordan Peele and Brian Huskey.

Nurse Beth enters a love triangle with Glenn and Owen and the doctors try to solve a high-stakes medical mystery.

Owen and Briggs work together on a murder case that has spanned fifteen years; a look into Owen and Briggs' past.

The cast appears on a morning show, "Up at 5," in order to promote the upcoming Childrens Hospital movie.

In a quest to get pregnant, Val assembles a team to break into Sy's sperm bank vault to steal his prized collection.

The doctors are summoned to the White House, by Lola, to help with a matter of national security.

Shocking DNA test results cause confusion and chaos among the staff.

After a newspaper calls him a "rock star surgeon," Glenn worries that he will die on his upcoming 27th birthday.

Glenn returns to Sao Paolo, Brazil, for his family's weekly Shabbat dinner.

Lola may have a superpower, and Blake and Dori seek parenting advice.

When Blake realizes that the source of his life's pain is the other doctors, he decides to take revenge.

Five years after leaving the army base, Owen must re-integrate into a 'normal' life at the hospital.

When Sy's new girlfriend makes significant changes around the hospital, the doctors react with hostility.

Sy runs himself ragged trying to impress an influential blogger before the big hospital fundraiser gala.